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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RYR3 All Species: 13.64
Human Site: Y1897 Identified Species: 33.33
UniProt: Q15413 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15413 NP_001027.3 4870 551932 Y1897 E E I R E E L Y D F H E D L L
Chimpanzee Pan troglodytes XP_514296 5018 570278 L2043 E E I R D Q L L D F H E D L M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536330 4972 565017 L1991 E E I R D Q L L D F H E D L M
Cat Felis silvestris
Mouse Mus musculus NP_808320 4888 554548 Y1916 E E I R E E L Y D F H E D L L
Rat Rattus norvegicus XP_001080527 4901 555534 Y1947 E E I R E E L Y D F H E D L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518548 2719 302048 A12 E C P H P P P A P L T V L H L
Chicken Gallus gallus NP_996757 4869 552752 Y1900 E E I R D E L Y D F H D D L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922113 4863 550481 Q1899 E E L Q E E L Q T F H N D L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24498 5127 580994 G2095 L E L R G R L G D F H D S L M
Honey Bee Apis mellifera XP_392217 5083 576621 N2054 E E L I S K M N E F H N N L M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.6 N.A. 68 N.A. 95.6 94.4 N.A. 45.3 87.5 N.A. 77.4 N.A. 45 45.5 N.A. N.A.
Protein Similarity: 100 80.9 N.A. 81.4 N.A. 97.5 96.7 N.A. 50.2 93.9 N.A. 87.9 N.A. 62.9 63.9 N.A. N.A.
P-Site Identity: 100 73.3 N.A. 73.3 N.A. 100 100 N.A. 13.3 86.6 N.A. 60 N.A. 46.6 33.3 N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 93.3 N.A. 100 100 N.A. 13.3 100 N.A. 73.3 N.A. 66.6 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 30 0 0 0 70 0 0 20 70 0 0 % D
% Glu: 90 90 0 0 40 50 0 0 10 0 0 50 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 90 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 90 0 0 10 0 % H
% Ile: 0 0 60 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 30 0 0 0 80 20 0 10 0 0 10 90 50 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 40 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 20 10 0 0 % N
% Pro: 0 0 10 0 10 10 10 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 20 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 70 0 10 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _